The deaths announced on Thursday mean 4,048 people have now died in the region's hospitals after contracting Covid-19.
While a total of 824 have died with the virus in the region's care homes.
In England, the NHS on Thursday recorded 289 new deaths in hospitals, bringing the death toll in the country's hospitals to 43,537.
Fourteen more deaths were confirmed at the University Hospitals of North Midlands NHS Trust, which runs County Hospital in Stafford and Royal Stoke University Hospital, taking the coronavirus death toll there to 709.
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A further five deaths were announced at the Sandwell and West Birmingham NHS Trust, which runs Sandwell General and City hospitals, where the death toll now stands at 600.
Four deaths were recorded at the Walsall Healthcare NHS Trust, which runs Walsall Manor Hospital, bringing the total there to 386.
Another two deaths were confirmed at the Royal Wolverhampton NHS Trust, which runs New Cross and Cannock Chase hospitals, where the total number of deaths rose to 401.
Two deaths were announced at the Dudley Group NHS Foundation Trust, which runs Russells Hall Hospital, where the death toll increased to 399.
While one death was recorded at the Birmingham Community Healthcare NHS Foundation Trust, where the total increased to 46.
And 11 deaths were confirmed at the University Hospitals Birmingham NHS Foundation Trust, which runs Queen Elizabeth, Heartlands, Good Hope and Solihull hospitals, where the total now stands at 1,452.
Elsewhere, two deaths were recorded at the Worcestershire Acute Hospitals NHS Trust, taking the total number of deaths there to 371.