The Birmingham singer and actress will play The Slade Rooms on a tour celebrating her 40 years in music.
Toyah, from Kings Heath, is best known for songs such as It's A Mystery, I Want To Be Free and Ieya.
She will play the city centre venue on November 2.
Special guests for the show are yet to be announced.
Tickets, priced at £22.50, are now on sale.
For more information, or to book, click here