Plans have been submitted for a road closure so the four cooling towers can be demolished.
It will be the last major demolition at the site which is being cleared to make way for 2,300 homes, commercial buildings and a school on site.
A school for more than 1,400 pupils proposed on the site has been handed Government funding.
Earlier this month a test blast was carried out in preparation for the demolition of the towers.
And in January a 600ft tall chimney was demolished at the site as part of the ongoing work.
A statement on the Rugeley Power Station's website says: "As part of preparations for the final major demolition activity at Rugeley Power Station with the controlled explosions of the four cooling towers, a road closure application is being submitted to the relevant authorities to propose that this will take place on Sunday 6th June 2021.
"Sections of the A51 near to Rugeley Power Station will be affected and a traffic management plan will be implemented to minimise local disruption. Further details will be provided once the final date has been confirmed and approved in the coming weeks."