Margot captured the hearts of the nation after her family's plea for a bone marrow donor. And last night her medical team gave her parents the news they have been waiting for.
Her latest blood tests show she now has 100 per cent donor cells - exactly four weeks after Margot, aged just 18 months, had her bone marrow transplant.
Margot's medical team have said it is 99 per cent certain she is 'disease free' - but the results of another test will confirm this early next week.
Her parents, Yaser and Vicki, originally from Essington, said they are thrilled with the news.
Yaser said: "This is the best news we could have hoped for at this stage. We are thrilled.
"The doctors have said that it is 99 per cent certain that there is no trace of leukaemia now but they have done another test which we will find the results of next week.
"We are sort of quietly hoping that this is the beginning of the rest of her life now."
On top of the fantastic news that was revealed last night, the latest tests also showed that her blood numbers have stopped falling and have started to climb, unassisted.
This means that her immune system is showing some signs of improving.