But while most teams have a dreadful record at Old Trafford in recent years, for Albion it’s been a very happy hunting ground. The Baggies have lost just once in their last five outings there – with Slaven Bilic’s side desperate to build on that run on Saturday.
Here we look back on what have been some thoroughly enjoyable trips to Manchester United.
September 28, 2013
Albion secured their first win at Old Trafford since 1978 thanks to goals from Saido Berahino and Morgan Amalfitano.
It was a composed chip from Amalfitano which sailed over David de Gea that put Steve Clarke’s side ahead. United were then fortunate to get back on terms when Wayne Rooney’s deflected free-kick caught out Boaz Myhill.
That sparked the game into life, Jonas Olsson hitting the bar and de Gea pulling off a superb one-handed stop to deny Amalfitano. But Albion got the win they deserved when Berahino found the corner with a fierce drive.
May 2, 2015
The Baggies secured their second successive victory at Old Trafford – and hit the 40-point-mark in the Premier League – thanks to an Olsson header. United dominated possession, but fell behind midway through the second half when Chris Brunt’s free-kick deflected in off the Swedish defender.
Louis Van Gaal’s side responded and won a penalty when Berahino handled Antonio Valencia’s cross. But Myhill made an outstanding save to deny Robin van Persie and claim the points.
November 7, 2015
Man United’s only win over Albion at Old Trafford in the last seven years arrived in November 2015.
Jesse Lingard curled home his first ever United goal to put Van Gaal’s side ahead early in the second half. Substitute Berahino then missed a superb opportunity to equalise.
But in stoppage time, Gareth McAuley was sent off for a late foul on Anthony Martial – with Juan Mata converting from the penalty spot.
April 1, 2017
It may not have been a win, but Albion battled their way to a clean sheet and solid point. Ben Foster was the hero, making two stunning saves to deny Marcus Rashford.
Albion went closest to scoring when De Gea spilled a long-range strike from Darren Fletcher on to the crossbar.
But overall, the result was based on solid defending, with the centre-back pairing of Jonny Evans and McAuley making 13 clearances each and a combined eight interceptions.
April 15, 2018
A Jay Rodriguez header not only saw Albion return to winning ways at Old Trafford, it also saw saw Manchester City crowned Premier League champions. Once again Foster was the hero, making outstanding stops to deny Romelu Lukaku.
And that gave Albion a platform to win the game with Rodriguez heading home a Brunt corner. The result saw United fall 16 points behind City with five games to play.