Clarke's side arrive at Prenton Park knowing that 2,000 Tranmere fans will be watching on as Merseyside was placed in Tier 2 of coronavirus restrictions.
It will be the first time Walsall have played in front of supporters since March and although Clarke is pleased to see some sort of normality return, he is aiming for an upset against in-form Rovers.
“It’s nice to see fans back – we can’t wait to get our own fans back," he said.
"That’s why we are in football, for the passion to watch the games and fans supporting their local team.
"It will be a strange feeling after such a long time without them but hopefully those 2,000 Tranmere fans will go home unhappy.
“They’re on a good run. We’re looking forward to going up there. Their confidence is high but we’ll be ready to go."
When asked whether having fans back tomorrow will help Walsall, despite being the away side, Clarke added: “I don’t really know. There’s only 2,000 and Tranmere have a big ground so I don’t know what 2000 is going to look like in Tranmere.
"Let’s speak about that after but we don’t worry about that, we’ve got to focus on ourselves and put in a performance.
"We went to Newport who are flying high and we go to Tranmere who are flying high so let’s see how the game goes but I don’t think it will make too much of a difference to be honest.”