Speaking ahead of Wednesday’s Premier League shareholders meeting, Purslow said it was unlikely proposals which would drastically alter the face of English football would have “much traction” among top flight clubs.
Liverpool and Manchester United have put forward a plan which would see the Premier League provide the cash-strapped EFL with a £250million bailout.
But it would also see the top flight reduced in size from 20 to 18 teams, with the so-called “Big Six” taking more control over how the division is run.
Purslow claims that is why the majority of clubs will be unable to support the plans in their current form.
He told Radio 4’s Today programme: “I think it is highly unlikely this plan is going to get much traction within the Premier League itself.
“It has come at a time of crisis, at a time when serious conversations are already underway between the Premier League and the government about how to address the short-term financial crisis and the long-term structural issues.
“There are elements in this plan which make great sense but in the short-term the priority is funding clubs that are in danger of going out of business.”
Purslow was also critical of EFL chairman Rick Parry, who took part in discussions with Liverpool and Manchester United without consulting the rest of the league.
He continued: “I think it is amazing the chairman of the Football League would have chosen to go live with a plan without discussing it with the rest of the league.
“The way to (engage) with the Premier League is to talk to the chairman and chief executive of that league through the front door.
“Not to head over to Florida or Boston and discuss it with only two Premier League teams.
"I expect there to be very honest, open and transparent dialogue among the 20 Premier League clubs."