Speaking during PMQs, Mrs May said her ambitious plans for the West Midlands would prove that the Government was intent on building an economy that 'works for everyone'.
She also backed Tory candidate Andy Street in his bid to become the region's mayor, describing him as 'the right person' for the job.
Responding to a question from Lichfield MP Michael Fabricant on her views on improving employment across the region, the Prime Minister said: "We have very strong ambitions to make the Midlands an engine for growth in the UK.
"That's why we have plans for the Midlands Engine that demonstrate that when we say we are going to build an economy that works for everyone we actually mean it.
"For the West Midlands, having the devolution deal and having the right person elected as mayor, who I think will be Andy Street, is absolutely crucial."