The visitor attraction, near Stourbridge, will be lit up at 8pm on Thursday.
Local production manager Ryan Barnsley at Ian Livie.com- Concert & Corporate Lighting, who normally provide specialist lighting equipment for stadium events and concerts, is providing the technology in recognition of NHS and other frontline who are fighting the coronavirus outbreak.
It is hoped the lit up visitor attraction will also remind people of the need to follow Government advice on social distancing.
The blue represents NHS workers, while the green is for social care staff, care providers, local government staff and those in the voluntary sector.
Mr Barnsley suggested lighting the historic cone after hearing about the Clap for Carers initiative, with help from a senior lighting engineer Luke Welch.
Mr Barnsley said: "As an international company, that travels all over the world to support concerts and events, it has been strange to have so much time at home and this is our way of saying thank you to the amazing nurses, doctors and care workers for all they are doing.
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"We are asking everyone to stay at home and keep safe and I hope our illuminations on the cone will remind frontline workers who might be passing after a shift that we stand with them every step of the way."
Dudley Council House and Himley Hall are also being lit up in blue and green every evening until further notice.
Councillor Ian Kettle, Dudley Council's cabinet member for regeneration and enterprise, added: "Iconic buildings all around the country are being lit up in blue and green in recognition of the selflessness of front line workers who are fighting to save lives and serve the people of our country.
"Now the Red House Glass Cone has joined that group by being lit up in blue and green this Thursday. I hope it will serve as reminder that we can all play our part in this crisis by staying home to save lives and protect the NHS.
"I would like to offer my personal thanks to all our residents who are playing their part, especially those on the front line, and of course to RBLX for lighting up the cone."