The deaths announced on Thursday means the total number of Covid deaths in hospitals across the region now stands at 7,585.
On top of this, a total of 1,405 people have died in the region's care homes after contracting coronavirus.
NHS England confirmed a further 21 deaths on Thursday, meaning 87,020 have died in the country's hospitals after testing positive for coronavirus.
Three deaths were reported at the Dudley Group NHS Foundation Trust, which runs Russells Hall Hospital, taking the total number of deaths to 740.
One death was recorded at the Royal Wolverhampton NHS Trust, which runs New Cross Hospital, where the total now stands at 801.
A further death was confirmed at the Walsall Healthcare NHS Trust, which runs Walsall Manor Hospital, where a total of 721 people have now died from coronavirus.
And one death was announced at the University Hospitals Birmingham NHS Foundation Trust, where 2,609 people have now died. The trust runs the Queen Elizabeth, Heartlands, Solihull and Good Hope hospitals.
There were no new deaths announced at either Sandwell and West Birmingham NHS Trust or University Hospitals of North Midlands NHS Trust, where the totals remain at 1,713 and 1,376 respectively.
A total of 42,864,836 vaccinations have been carried out across England to date – including first and second doses.
In the Midlands, 5,606,423 first doses of the coronavirus vaccine has been administered, while 2,556,311 second doses have been carried out.
The data includes vaccinations carried out between December 8 and May 5.