The deaths announced on Friday mean 7,346 people have now died with the virus in the region's hospitals.
On top of this, a further 1,356 have died in the region's care homes after contracting coronavirus.
NHS England confirmed a further 174 deaths on Friday, meaning 84,091 people have now died in the country's hospitals after testing positive for Covid-19.
Three deaths were announced at the Walsall Healthcare NHS Trust, which runs Walsall Manor Hospital, where the death toll increased to 706.
Two deaths were recorded at the Sandwell and West Birmingham Hospitals NHS Trust, which runs City and Sandwell General hospitals, where 1,130 people have now died with Covid.
A further two deaths were announced at the Royal Wolverhampton NHS Trust, meaning the death toll at New Cross Hospital increased to 779.
Two deaths were reported at the University Hospitals of North Midlands NHS Trust, which runs the main hospitals in Stafford and Stoke, taking the trust's death toll to 1,343.
Another two deaths were announced at the Dudley Group NHS Foundation Trust, which runs Russells Hall Hospital, where the total increased to 705.
And three deaths were recorded at the University Hospitals Birmingham NHS Foundation Trust, which runs Queen Elizabeth Hospital as well as Heartlands, Solihull and Good Hope hospitals, taking the death toll there to 2,525.
Two deaths were reported at the Worcestershire Acute Hospitals NHS Trust.
A spokesman for NHS England said: "A further 174 people, who tested positive for coronavirus (Covid-19) have died, bringing the total number of confirmed reported deaths in hospitals in England to 84,091.
"Patients were aged between 26 and 102 years old. All except six – aged 61 to 89 years old – had known underlying health conditions.
"Date of death ranges from April 13, 2020, to March 4, with the majority being on or after March 1.
"Their families have been informed."
Meanwhile, 18,835,355 coronavirus vaccinations have been carried out across England to date – including first and second doses.
In the Midlands, 3,527,175 first doses of the coronavirus vaccine has been administered, while 126,482 second doses have been carried out.
The data includes vaccinations carried out between December 8 and March 4.