The deaths announced on Wednesday mean 7,314 people have now died with the virus in the region's hospitals.
On top of this, a further 1,356 have died in the region's care homes after contracting coronavirus, after 17 new deaths were announced on Tuesday. Six deaths were announced in Staffordshire, four in Sandwell, three in Dudley, two in Birmingham, one in Walsall and one in Wolverhampton.
NHS England confirmed a further 204 deaths on Wednesday, meaning 83,733 people have now died in the country's hospitals after testing positive for Covid-19.
One death was confirmed at the Dudley Group NHS Foundation Trust, which runs Russells Hall Hospital, where the total increased to 703.
Four deaths were announced at the Sandwell and West Birmingham Hospitals NHS Trust, which runs City and Sandwell General hospitals, where 1,125 people have now died with Covid.
Two deaths were reported at the University Hospitals of North Midlands NHS Trust, which runs the main hospitals in Stafford and Stoke, taking the trust's death toll to 1,339.
Two deaths were recorded at the Royal Wolverhampton NHS Trust, meaning the death toll at New Cross Hospital increased to 776.
No further deaths were confirmed at the Walsall Healthcare NHS Trust, which runs Walsall Manor Hospital, where the death toll remains at 700.
Five deaths were announced at the University Hospitals Birmingham NHS Foundation Trust, which runs Queen Elizabeth Hospital as well as Heartlands, Solihull and Good Hope hospitals, taking the death toll there to 2,513.
One death was reported at the Worcestershire Acute Hospitals NHS Trust.
A spokesman for NHS England said: "A further 204 people, who tested positive for the Coronavirus (Covid-19) have died, bringing the total number of confirmed reported deaths in hospitals in England to 83,733.
"Patients were aged between 32 and 100 years old. All except seven (aged 63 to 88 years old) had known underlying health conditions.
"Date of death ranges from 2 January to 2 March 2021 with the majority being on or after 27 February.
"Their families have been informed."
Meanwhile, 18,194,919 coronavirus vaccinations have been carried out across England to date – including first and second doses.
In the Midlands, 3,428,512first doses of the coronavirus vaccine has been administered, while 103,782 second doses have been carried out.
The data includes vaccinations carried out between December 8 and March 2.