The deaths announced on Monday mean 7,127 people have now died with the virus in the region's hospitals.
On top of this, 1,289 people have died in the region's care homes after contracting coronavirus.
In figures from NHS England on Monday, a further 178 deaths were confirmed in the country's hospitals – taking the total to 81,482.
A further eight deaths were confirmed at the Sandwell and West Birmingham Hospitals NHS Trust, where 1,080 people have now died with Covid.
Three deaths were reported at the Dudley Group NHS Foundation Trust, which runs Russells Hall Hospital, meaning the death toll there rose to 687.
Three deaths were announced at the Walsall Healthcare NHS Trust, meaning 680 Covid patients have now died at Walsall Manor Hospital.
One death was recorded at the Royal Wolverhampton NHS Trust, taking the death toll at New Cross Hospital to 759.
A further death was confirmed at the University Hospitals of North Midlands NHS Trust, which runs the main hospitals in Stafford and Stoke, taking the trust's death toll to 1,314.
Five deaths were reported at the University Hospitals Birmingham NHS Foundation Trust, which runs Queen Elizabeth Hospital as well as Heartlands, Solihull and Good Hope hospitals, taking the death toll there to 2,452.
A spokesman for NHS England said: "A further 178 people, who tested positive for coronavirus (Covid-19) have died, bringing the total number of confirmed reported deaths in hospitals in England to 81,482.
"Patients were aged between 25 and 101 years old. All except seven – aged 47 to 97 years old – had known underlying health conditions.
"Date of death ranges from January 2 to February 21 with the majority being on or after February 18.
"Their families have been informed."
Meanwhile, 15,471,509 coronavirus vaccinations have been carried out across England to date – including first and second doses.
In the Midlands, 2,881,310 first doses of the coronavirus vaccine has been administered, while 77,777 second doses have been carried out.
The data includes vaccinations carried out between December 8 and February 21.