A total of 46 deaths were announced in the region's hospitals by the NHS on Tuesday, while 32 more deaths were confirmed in care homes.
It means a total of 5,046 have now died in the region's hospitals after contracting the virus, while 955 have died in care homes.
Meanwhile the UK-wide death toll increased by 1,243 to 83,203 on Tuesday - the second highest daily rise since the pandemic began.
The only day when more deaths were recorded was last Friday, when 1,325 were announced.
The care home deaths are updated weekly by the Office for National Statistics.
The latest figures showed the biggest rise in Staffordshire, where 19 more care home deaths were confirmed making a new total of 342.
Nine more care home deaths were confirmed across the Black Country, making a total of 378, and four were announced in Birmingham meaning 235 people have died with Covid-19 in the city's care homes.
However care home deaths have only been recorded since April 10 - one month after the first hospital Covid death in the West Midlands, meaning the full total is likely to be higher.
A further seven deaths were recorded at the University Hospitals of North Midlands NHS Trust, which runs County Hospital in Stafford and Royal Stoke University Hospital, taking the coronavirus death toll there to 1,007.
Twelve deaths were announced at the Royal Wolverhampton NHS Trust, which runs New Cross and Cannock Chase hospitals, where the total stands at 495.
A further four deaths were confirmed at the Walsall Healthcare NHS Trust, which runs Walsall Manor Hospital, where the total stands at 469.
Six deaths were recorded at the Sandwell and West Birmingham NHS Trust, which runs Sandwell General and City hospitals, where 712 people have now died.
Nine deaths were announced at the Dudley Group NHS Foundation Trust, which runs Russells Hall Hospital, where the death toll now stands at 481.
While no more deaths were announced at the Midlands Partnership NHS Foundation NHS Trust, where the death toll remains 44.
And eight deaths were confirmed at the University Hospitals Birmingham NHS Foundation Trust, which runs hospitals across Birmingham including the Queen Elizabeth Hospital, meaning the toll now stands at 1,759.