It brings the total number of Covid-19 patients who have died in hospital in the region to 2,796.
A further 192 patients died in hospitals across England in figures announced on Thursday, taking the total to 32,484.
Four patients were confirmed to have died at the Sandwell and West Birmingham Hospitals NHS Trust, which runs Sandwell General and City hospitals, with the death toll rising to 424.
At the Walsall Healthcare NHS Trust, which runs Walsall Manor Hospital, a further four patients died taking the overall total to 247.
A further two patients died at the Dudley Group NHS Foundation Trust, which runs Russells Hall Hospital, where the total is now 283.
While two people died at the University Hospitals of North Midlands NHS Foundation Trust, which runs Stafford County and Stoke Royal hospitals, bringing the trust's total to 392.
One patient died at the The Royal Wolverhampton Trust, which runs New Cross and Cannock Chase hospitals, where the total is now 307.
And 10 patients died at the University Hospitals Birmingham NHS Foundation Trust, which runs Queen Elizabeth, Heartlands, Good Hope and Solihull hospitals, where the total rose to 1,073.
A spokesman for NHS England said: "A further 192 people, who tested positive for the coronavirus (Covid-19) have died, bringing the total number of confirmed reported deaths in hospitals in England to 32,484.
"Patients were aged between 27 and 101 years old. All except one – aged 63 – had known underlying health conditions.
"Date of death ranges from March 27 to October 28, with the majority being on or after October 25.
"Their families have been informed."