It brings the total number of Covid-19 patients who have died in hospital in the region to 2,745.
Four patients were confirmed to have died at the University Hospitals of North Midlands NHS Trust, which runs Stafford County and Stoke Royal hospitals, bringing the trust's total to 383.
At the Sandwell and West Birmingham NHS, which runs Sandwell General and City hospitals, a further two patients died taking the total to 414.
One further death was also reported at the Royal Wolverhampton NHS trust, which runs New Cross Hospital, taking the total to 305.
At the Dudley Group NHS Foundation Trust, which runs Russells Hall Hospital, one more patient has died bringing the total there to 278.
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And five more patients have died at the University Hospitals Birmingham NHS Trust, which runs Queen Elizabeth, Heartlands, Good Hope and Solihull hospitals, where the death toll is now 1,055.
In total a further 91 coronavirus patients were today confirmed to have died in hospitals across England, taking the total to 31,910.
The UK-wide death toll released by the Government is yet to be announced.
A spokesman for NHS England said: "A further 91 people, who tested positive for coronavirus (Covid-19) have died, bringing the total number of confirmed reported deaths in hospitals in England to 31,910.
"Patients were aged between 44 and 95 years old. All had known underlying health conditions.
"Date of death ranges from September 24, to October 25, 2020, with the majority being on or after October 23.
"Their families have been informed."