Florence Crowther, aged 10 from Wolverhampton, was diagnosed with type-one diabetes in 2018.
During lockdown, decided she wanted to inspire people to get fit and raise diabetes awareness.
She and her classmates from the Royal School will be holding a sponsored bounce on February 3, taking place over Zoom and aiming to raise £1,000.
Mum Rebecca Crowther, 39, said: "She was diagnosed out the blue, upturned our lives but we have learned to live with it and she is coping very well.
"Florence has done a lot of reading and she is very knowledgeable about her condition; she feels like there is not a lot of awareness of diabetes in children, I didn't even know children could get it.
"Along with all of her friends in year five, Florence is doing an hour long sponsored bounce over Zoom for JDRF, a charity who is trying to find a cure for diabetes in children, I hope in Florrie's lifetime they will find a cure."
Due to Florence's diabetes, exercise can cause her to go into 'hypo', however this has not deterred her, she said: "I will just have some sweets or apple juice and keep going."
Rebecca added: "We try to do something for charity every year, but this year it is a cause closer to our hearts.
"Once has completed her challenge she will make a short video where she hopes to raise awareness about diabetes in children and encourage others to go to their doctor if they show any of the signs.
"We set a fundraising target of £1,000, but I know times are really tough, so any donation is very generous and it all helps."
To donate to Florence's appeal visit Rebecca's Just Giving page.