The 26-year-old man was found with a serious injury in Shyltons Croft, Ladywood, just before 4.20am.
He was pronounced dead at the scene.
West Midlands Police officers are in the early stages of their investigation and are appealing for witnesses to come forward so they can establish the circumstances around the man's death.
Detective Chief Inspector Stuart Mobberley, from the homicide team, said: "A young man has tragically lost his life and our thoughts are with his loved ones at this terrible time.
"We will leave no stone unturned in our enquiries as we try to establish what went on earlier this morning.
"I would urge anyone with information which will assist to get in touch as soon as possible."
Anyone with information can call West Midlands Police on 101, quoting log number 316 of April 22.
They can be contacted via live chat or by calling 101, quoting log 316 of 22 April.
Alternatively, contact Crimestoppers anonymously on 0800 555111 or at crimestoppers-uk.org