The two men, aged 18 and 22 years old, both from the Dudley area, were arrested today.
They remain in police custody this afternoon.
Mr Cox died outside The Clifton pub in Sedgley just before midnight on August 15. He was found with fatal head injuries.
A total of five men have been charged so far and all appeared at Wolverhampton Crown Court on Monday.
Wayne Burke, 22, of Queens Street, Pensnett; Shane Jones, 25, of Orchard Grove, Lower Gornal; Shaquel Halliday, 22, of Shadwell Drive, Lower Gornal; and Adam Ashwin, 19, of Monument Lane, Sedgley, have all been charged with Reece’s murder, as well as violent disorder and actual bodily harm.
A fifth man, Tyrone Halliday, aged 24 also from Shadwell Drive, was charged with violent disorder and actual bodily harm.
A West Midlands Police spokesman said: "Enquiries continue and anyone with information is asked to contact us."
Anyone with information can call West Midlands Police on 101, quoting incident reference number 20BW/143529D/20.
Alternatively, contact Crimestoppers anonymously on 0800 555111 or at crimestoppers-uk.org
More than £10,700 has so far been raised in an online crowdfunding appeal for Mr Cox's family and son, and a charity walk has been organised to honour Mr Cox.