The men fell for Kate Pattinson's claims at the massage parlour where she worked.
A court heard her clients became infatuated with Pattinson after visiting her at the brothel in Fenton, Staffordshire, and stumped up thousands of pounds after falling for her story.
She fleeced a 70-year-old pensioner out of £65,561 and another 56-year-old man was tricked into handing over £10,000. She is now behind bars.
Stoke-on-Trent Crown Court heard that the 33-year-old Pattinson, of Edward Street, Dudley, used the cash to pay off drug debts as well as treating herself to a boob job and holidays abroad.
The drug addict was arrested after one of her victims reported her to police after his life savings were plundered by her.
Pattinson was jailed for 32 months after admitting two charges of fraud.
Passing sentence, Judge David Fletcher said: "These were two vulnerable people. You very quickly wiggled your way into their affection.
"They thought you liked them, they even thought you loved them. To say you had lost two of your relatives is appalling."
The court heard £65,561 was paid by the 70-year-old pensioner, whose wife had died of cancer.
He paid Pattinson for sex at the massage parlour and she later visited him at his home so she did not have to pay the parlour any commission.
The man gave her cash for food, to pay her bills, and funded trips for her children. She then started asking for money to pay off debts.
Miss Fiona Cortese, prosecuting, said: "She said her mother had died and was waiting for inheritance from her mother's estate. He gave her the money because he believed her. He believed they were in a relationship and she had personal belongings at his house."
The second victim was a man, 56, who has Parkinson's Disease.
The court heard he fell in love with Pattinson after meeting her at the massage parlour.
He paid for her holidays, some of her bills and repaid a loan after cashing in premium bonds and money inherited from his father's death.
Miss Cortese added: "She told him her grandmother had died and she was due to receive £78,000. She began to ask for money.
"She was given the money on the understanding she would pay it back. He gave her his debit card and his pin number."
Pattinson was arrested in July when she returned from a holiday in Egypt where police found most of the cash was handed to a drug dealing loan shark.
Mr Andrew Turnock, defending, said: "Both individuals have been blinded to some extent by the opportunity of sexual gratification by a woman far much younger than they.
"She accepts she took advantage of these two individuals."
One of the victims, who did not wish to be named, said after the case: "She told me she was not a drug addict and she said she loved me and I fell for it. It is deplorable that she said her grandmother had died.
"I am devastated."