The new Amazon Small Business Accelerator initiative was announced at Birmingham Tech Week and will be open for applications until November 10.
The businesses will get free education to help get their products online.
The bootcamp on November 17 and 18 will give businesses access to practical sessions on how to get online, master social media, sell products on Amazon and achieve scale.
Successful firms will also be able to network online with a group of local founders and access Amazon specific training and advice from a dedicated group of experts and advisers.
To apply firms must fill in the form at www.enterprisenation.com/accelerator and successful businesses will be notified by November 12.