The Marriott hotels group’s lifestyle boutique brand Moxy Hotels has opened at the exhibition attraction.
A 224-bedroom hotel opened on Wednesday.
Moxy Birmingham NEC is filled with stylish nods to the music industry in its interior design.
It is within walking distance of the NEC, where the Resorts World Arena hosts some of the world’s most famous bands and musicians.
The hotel has created 21 jobs and is being run by management group Belvar.
Donovan Sumner, director of operations at Belvar, said: "This will be our ninth UK opening in just over three years. The NEC is a great destination, alive and buzzing with events on a daily basis."