A nationwide survey of 2,000 British workers, commissioned by The National Lottery, showed that the lockdown had led to West Midland folk reconsidering their lifestyles.
It found that 24 per cent of people in the region had brought them to the conclusion they were not in a 'worthwhile' career.
On the positive side, it found that a quarter of people would carry on doing their jobs, even if the won tonight's Euromillions £126 million rollover jackpot.
Nearly seven in 10 of those polled in Birmingham and the Black Country said they now thought life was too short to be working in a job they hated, with 34 per cent saying the restrictions had made them realise they weren't appreciated in their jobs.
The most popular alternative careers for people in the area were in the medical or care professions, with 28 per cent saying they wanted to retrain as a doctor, nurse, midwife or carer.
A further 13 per cent wanted to become a gardener, 12 per cent a teacher and seven per cent said lockdown had made them realise they would now like to become a YouTube star.
It also found that 28 per cent identified having a good work-life balance as a priority.
The National Lottery study also found that the biggest barriers to changing careers for people in Birmingham and The Black Country include not having the necessary funds (41 per cent) and a lack of confidence (38 per cent).
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Just over three quarters said the events of 2020 had also made them reconsider their lifestyle and priorities.
Six in 10 people in the area said they hoped to become healthier, 44 per cent said lockdown made them realise the importance of spending time with loved ones, and 31 per cent said they would love to travel the world as soon as it is possible.
A total of 30 per cent said they would start their own business if they won big and 25 per cent would retrain for their dream job. Just under four in 10 would learn a new trade, with 18 per cent retraining to become a charity worker, and 17 per cent hoping to become a pilot.
Andy Carter of lottery operator Camelot said the events of this year seems to have left many of people wanting more from their jobs, thinking about what their next career move might be or giving it all up to do something they loved.
“Our passion for gardening and cooking in lockdown and months of home-schooling has clearly inspired the nation to consider a career overhaul and realise the importance of job satisfaction," he said.