Leaders from different faiths, along with parliamentary candidates and people wanting to pay their respects lit a candle in memory of the 22 people, including children as young as eight, who were killed by a suicide bomber at the Manchester Arena on Monday night.
Organised by Interfaith Wolverhampton, people gathered at the event ast St John's church in the city centre to listen to tributes and moving speeches.
Organiser and Interfaith chairman Parveen Brigue, said: "I'm really touched by how many people turned up to the vigil.
"All attacks of terrorism are cowardly attacks on innocent people, but this attack stands out for its appalling, sickening cowardice, deliberately targeting innocent defenceless children and young people who should have been enjoying one of the most memorable nights of their lives.
"It just goes to show how people all over Wolverhampton can come together in times like this.
"It could have happened to anyone or anywhere, but we are as one."
Wolverhampton parliamentary candidates Emma Reynolds and Pat McFadden also attended the vigil.
She said: "It's good to see Wolverhampton coming together."
Mr McFadden added: "The vigil is important here in Wolverhampton and around the country.
Christine Poole, 59, was one of those at the vigil.
She said: "I still haven't quite come to terms with what happened on Monday night. It's absolutely awful and I can't fathom how anyone could do such a thing.
"Whenever I think about those families that have lost loved ones, my heart breaks.
"The vigils held across the country remind us that the world is not a bad place and they're extremely important."