Thousands of screaming, hysterical girls – and plenty of mothers too – sung their hearts out to Everybody in Love, Love You More, She Makes Me Wanna and One Shot among many others.
The boys are currently on a farewell tour after recently announcing their shock split.
For the majority of the capacity LG Arena crowd it would be a final goodbye as the group's tour finishes later this month.
Read the review of JLS in Birmingham on Native Monster
Aston, JB, Marvin and Oritse performed for almost two hours, ending with Everybody in Love.
In amongst the frenzied crowd was Kidderminster teenager Holly Gualano, who said she wept for two days when she heard the boys were breaking up.
And there were more tears last night as she cried, screamed and sang her way through the show.
The 14-year-old, who was at the gig with her 13-year-old friend Chloe Arnold, said: "It was absolutely brilliant."
"We were by the second stage and I could almost touch them.
"I cried for two days when I heard they split up and was on the phone for three hours to get tickets.
"I just think they're such nice boys, I love them."
Dudley mother Leander Harding was seeing the group for a 10th time.
As well as gigs she has attended Christmas lights switch-ons and book signings with her daughter Georgia to get close to the boys.
The pair and their friends arrived in style in a pink limousine.
Mrs Harding said: "My daughter loved them on the X Factor and we've been to see them all over the place.
"I'm waiting for the tears."
After the show 13-year-old Dormston School pupil Georgia said her favourite moment of the gig was when Aston – whom the group had single out as their favourite earlier for his 'pretty boy face' - ripped his shirt off.
"It was really good, we had a great night and I got right next to the barrier at the front," she said.
"They finished with Everybody in Love and that was the best song."
Warwick girl Steph Dagnall was seeing the group for the ninth time along with sisters Heather, 12, Abigail, eight and Aimee McCarthy, 12.
The 16-year-old said of her love for the band: "They're amazing, Aston's the best. And they're all hot."
Lichfield trio Lucy Birchall, aged 12, Georgia Allen, 12 and Isabelle Smith, 10, painted the group's names on their faces in preparation for the gig.
Georgia said: "They're just a great group. I love them."
As well as their adoring fans it seems JLS enjoyed the gig too.
Afterwards Oritse tweeted:
The group will bow out for good at the O2 Arena in London on December 22.