The first items are due to go on sale online in the next couple of months.
Birmingham 2022 and CGF Partnerships have appointed Cube International, with offices in both Herefordshire and Worcestershire, as the master licensee responsible for designing, sourcing, delivering and retailing licensed products.
Around 1,500 products will be developed and sold, featuring Birmingham 2022, Commonwealth Sport and Home Nations branding.
A first phase of merchandise, including hoodies and T-shirts, mugs, water bottles and pin badges will go on sale online in the next couple of months.
Cube International will also create exclusive ranges for the Birmingham 2022 official mascot, which will be unveiled later this year.
Around 35 official retail stores will be set up, including a Birmingham city centre megastore, and at a number of other city centre locations, transport hubs, Games venues and temporary live sites.
The retail stores will employ around 300 people, with staff recruited where possible with the support of the Commonwealth Jobs and Skills Academy, launched by the West Midlands Combined Authority to generate job opportunities for and improve the skills of local people.
Roles will include customer service, security and warehousing positions.